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Polly Leilei Chen

Polly Leilei Chen

Principal Investigator
Cancer Science Institute of


Dr. Polly Chen is an Assistant Professor in the Department of Anatomy and a principle investigator at the Cancer Science Institute of Singapore, National University of Singapore where she directs a research lab studying human cancers, particularly liver cancer. Her group currently focuses on the identification of key RNA editing events and translating these findings into diagnoses and even treatment. In addition, she has begun collaborating with local and international researchers to study the roles of RNA editing enzyme ADARs and their substrates in different types of human cancers, such as esophageal squamous cell carcinoma (ESCC), Gastric cancer and acute myeloid leukemia (AML).

Research Interest

Hepatocellular carcinoma (HCC), Transcriptome instability of human cancers, Regulation of tumorigenesis by transcriptome instability.