3^rd Global Summit on Oncology & Cancer May 06-07, 2019 Tokyo, Japan

In today’s very, complex healthcare environment where a patient will easily interact with multiple care givers during their course of care/treatment and delivery. The key common issue for any harm or potential injury to the patient is Poor or Lack of CLEAR Communication. This presentation will review some simple ways to improve communication between the care giver and the patient/family, review the risks or outcome of care resulting from unclear communication and highlight some global solutions toward achieving a better improved communication plan between the patient and the provider.  JCI standard references will be incorporated as potential tools or possible requirements to be adopted by an organization as a guide for clearer forms of communication. Discussion during the presentation will highlight the one area during care where a clear level of communication and listening from both the patient and the care giver is crucial – that being at the point of DISCHARGE.  This is such an important step in the delivery of continuity of care but is often done very quickly and with very little follow up on the understanding of the discharge planning recommended. There will be a review of the types of Channels of Communication (either Verbal or Written) which is seemed to give the best outcome and when it is appropriate to utilize a certain channel of communication. The presentation will highlight the common causes of failures and demonstrate some of such failures which occur on a day to day basis globally with the use of JCI “International Patient Safety Goals” which could affect the course of care for the cancer patient during their treatment. There will be reference to a “white paper” which addressed the common issues of potential harm due to lack of clear and simple communications. These findings from the white paper will be linked to how one can identify the common barriers within an organization that fosters the lack of good communication. In addition, to the identification of the barriers, there will be time spend on review of the impact and challenges which will result in poor communication such as longer length of stay – increased medication errors – potential infections due to lack of understanding on basic prevention techniques – lack of required follow-up care, these are just a few of the potential impacts/challenges that are possible unsafe and non-quality outcomes resulting in RISK to the patient. Focus will be on medical orders and critical test results – cultural barriers – language issues – aging patient population – and how the international JCI standards could be use as a tool for monitoring the level of communication between the care giver and the patient to achieve a ZERO HARM outcome of care.

 

State of art radiotherapy has ability to deliver highly conformal doses of radiation that can target large tumors and avoid normal tissues with high precision; however, the limitations of conventional online imaging hinder this technology from achieving its true potential. Advances in MR imaging allow non-invasive assessment of morphological, biological and functional process in tissue and therefore, may provide tools for early assessment and prediction of tumors and normal tissue responses to irradiation. Imaging and pathological information combined from a larger patient cohort can be used to develop a predictive model. Superior soft tissue visualization combined with the MR Guided Radiation Therapy (MRgRT) ability to dynamically adjust the treatment plan and or gate the treatment delivery to account for inter/intra-fractional anatomical changes offers great promise to further enhance treatment precision for abdominal and thoracic anatomical sites. Tumors are not uniform within a volume, which may be responsible for the variable outcomes from the same therapy among patients. Tumors heterogeneity sub regions (habitats) shown by spatial distributions of MR images define distinct physiologies such as viable cells, necrosis and oedema and could provide information for therapeutic decision support. Advances in MRI can also assist in obtaining images that reflects underlying pathophysiology and that these relationships can be revealed via. quantitative image analyses.

 

Current drug treatments for pancreatic cancer fail to effectively prolong survival and are often limited by dose-related toxicity in patients. Traditional school of chemotherapy focuses upon eradication of tumor cells, causing systemic side effects due to collateral damage in non-malignant normal cells of the host. Contemporary chemotherapeutic approach also considers the Tumor-Micro Environment (TME) when choosing new molecular targets, aiming to impede tumor progression by maintaining optimal tumor-microenvironment interactions. TME comprises tumor cells, endothelial cells, TumorAssociated Macrophages (TAM), inflammatory and immune cells, as well as stromal factors such as Extracellular Matrix (ECM). Experimental data have demonstrated the role of these individual components in promoting tumor growth and progression. During epithelial-mesenchymal transition, cell-ECM interactions would reorganize the cytoskeleton to increase the migratory activity and invasiveness of cells, facilitating tumor progression and metastasis. Besides, macrophages in tumor inflammatory microenvironment could release vasoactive mediators like VEGF and chemokines that together promote tumor angiogenesis. In addition, tumor immunity could also be triggered due to anti-tumoral T cell responses that kill tumor cells by the CD8 cytotoxic T-lymphocyte recognizing major histocompatibility complex class I restricted antigens expressed on the surface of tumor cells. Here, the tumor-targeting ability of test drugs with the potential to induce tumor immunity reprogramming will be illustrated. Taken together, effective control of the tumor microenvironment may open up a brand new field for contemporary anti-tumor chemotherapy. Discovery of novel agents that possess target-specific anti-tumorigenic potential through distinctive mechanism while concomitantly modulating the tumor microenvironment would largely provoke pancreatic cancer chemotherapy efficacy.

 

Salam Azad  is a freelance Writer and President of Soheli Mirza Cancer Foundation. Azad had raised the issue of Islamist fundamentalism. Madrasa (Islamic School) education and the practice of issuing fatwa. A fearless writer, continues to crusade against injustice committed by Bangladesh society and government, particularly the failure to protect the rights of the minorities.

 

What is the cause of cancer? Genetic, food habit, smoking etc?  Nobody knows actual cause of Cancer. If know, medicine for cure of Cancer invented and thousand of man-women-children can able to survive. Suspected some of cause, like smoking. If the cause of lunch cancer of smoking. Why not stop from all over the world cultivation of tobacco? Awareness better than treatment. If a person is well aware about cancer, her / his malignancy diseased can detect early or earliest. Early detection means extending her / his life. Before operation or starting the treatment protocol it is mandatory to find the stage of malignancy. If stage crosses two please don’t go to operation or don’t give the patients any kind of treatment protocol. Because sometimes Chemotherapy more harmful, than cancer. Chemotherapy kills immunity of human body, Chemotherapy kill or reduce WBC etc. We know post operation Cancer cell are increasing multiply method. I repeated before operation it is mandatory that diagnosis the stage of malignancy. If Cancer patients cross the stage two please don’t go to operation or apply on his/her this kind of costly treatment. You simply ask what she / he like and love. If patients love to religion practices, please allow. If patients feel singing song or lessening song, please allow. If Cancer patients interested to read or write, please allow. If Cancer patients interested to love birds, trees, blue sky, moon, rain or any others natural beauty, please allow. That is the treatment of his / her, which one he / she love or like. Cancer patients able to pass peaceful few time, few month or few year. Without torture of operation, torture of treatment protocol, like Chemo therapy, Radio therapy, Immunotherapy etc. I heartily recommend about recherché. Recherché can find out proper way, only recherché can invent that medicine; which one cures Cancer. I submit humble request to leading country and prominent organization all over the World, please give more and more allocation and donation for invent Medicine for the cancer cure.